Substance

Nilotinib

Brand name:
Tasigna

Description

 
Chemotherapy
 
Tasigna effectively inhibits the tyrosine kinase activity of the BCR-ABL oncoprotein of cell lines and leukemia cells primarily positive on the Philadelphia chromosome
Brands:
Tasigna
Availability:
Prescription needed
Pregnancy:
Consult a doctor
Alcohol:
Not detected with light alcohol consumption
Side Effects:
Troubled Breathing With Exertion, Lower Back Or Side Pain, Bleeding Gums
Interactions:
Hepatic Impairment, Sprycel (dasatinib), Oxycodone
For informational purposes only. Consult your local medical authority for advice.

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Before taking Tasigna

You should not use nilotinib if you are allergic to it, or if you have:

  • low blood levels of potassium or magnesium; or
  • a heart rhythm disorder called long QT syndrome.

Tell your doctor if you have ever had:
heart disease, heartbeat problems, or long QT syndrome (in you or a family member);
a stroke;

  • blood circulation problems in your legs;
  • bleeding problems;
  • low blood levels of potassium or magnesium;
  • severe problems with lactose (milk sugar);
  • liver disease;
  • pancreatitis; or
  • surgical removal of your stomach (total gastrectomy).

You may need to have a negative pregnancy test before starting this treatment.
Do not use nilotinib if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using nilotinib and for at least 14 days after your last dose.
Do not breast-feed while you are taking nilotinib and for at least 14 days after your last dose.

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